BDBM50309833 (S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide::CHEMBL597477

SMILES NC(=O)[C@H]1CCCc2c1[nH]c1ccc(Cl)cc21

InChI Key InChIKey=FUZYTVDVLBBXDL-VIFPVBQESA-N

Data  2 IC50

PDB links: 6 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309833   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Institute Of Psychiatry And Neuroscience Of Paris

Curated by ChEMBL

LigandBDBM50309833((S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-car...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Institute Of Psychiatry And Neuroscience Of Paris

Curated by ChEMBL

LigandBDBM50309833((S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-car...)Copy SMILESCopy InChI

Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI