BDBM50310217 7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)-2-(1-oxypyridin-3-yl)-pyrazolo[1,5-a]pyrimidine::CHEMBL599326

SMILES [O-][n+]1cccc(c1)-c1cc2nccc(-c3ccc(OC(F)F)c(OCC4CC4)c3)n2n1

InChI Key InChIKey=WEZKAVBVBABLRE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50310217   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50310217(7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50310217(7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50310217(7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...)
Affinity DataEC50:  1.61E+3nMAssay Description:Inhibition of human PDE4D in U937 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed