BDBM50310485 (R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(tetrahydro-2H-pyran-4-yl)acetamide::CHEMBL1077829
SMILES CCOc1ccc(cc1)-n1c(nc2ncccc2c1=O)[C@@H](C)N(C1CCOCC1)C(=O)Cc1ccc(F)c(c1)C(F)(F)F
InChI Key InChIKey=OKJKFRMADNUCPQ-LJQANCHMSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50310485
Affinity DataIC50: 162nMAssay Description:Antagonist activity against human CXCR3 expressed in human PBMC assessed as inhibition of cell migration in response to ITAC in plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]-1P10 from human CXCR3 expressed in PBMC after 2 hrs in RPMI buffer by scintillation countingMore data for this Ligand-Target Pair