BDBM50311019 CHEMBL1078364::N-(cyanomethyl)-2-methoxy-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide

SMILES COc1cc(ccc1C(=O)NCC#N)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1

InChI Key InChIKey=OGYJYBMWSHOXRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311019   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311019(CHEMBL1078364 | N-(cyanomethyl)-2-methoxy-4-(2-(4-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311019(CHEMBL1078364 | N-(cyanomethyl)-2-methoxy-4-(2-(4-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed