BDBM50311288 CHEMBL1078785::N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide

SMILES Clc1ccccc1NC(=O)c1cnn2ccccc12

InChI Key InChIKey=CPQRFZBWMKEHSA-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311288   

TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311288(CHEMBL1078785 | N-(2-chlorophenyl)pyrazolo[1,5-a]p...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50311288(CHEMBL1078785 | N-(2-chlorophenyl)pyrazolo[1,5-a]p...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50311288(CHEMBL1078785 | N-(2-chlorophenyl)pyrazolo[1,5-a]p...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of full length RIPK2 (unknown origin) pretreated for 30 mins followed by ATP addition measured after 2 hrs by ADP-d2 tracer based fluoresc...More data for this Ligand-Target Pair