BindingDB logo
myBDB logout

BDBM50311288 CHEMBL1078785::N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide

SMILES: Clc1ccccc1NC(=O)c1cnn2ccccc12

InChI Key: InChIKey=CPQRFZBWMKEHSA-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311288   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311288
PNG
(CHEMBL1078785 | N-(2-chlorophenyl)pyrazolo[1,5-a]p...)
Show SMILES Clc1ccccc1NC(=O)c1cnn2ccccc12
Show InChI InChI=1S/C14H10ClN3O/c15-11-5-1-2-6-12(11)17-14(19)10-9-16-18-8-4-3-7-13(10)18/h1-9H,(H,17,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair