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BDBM50311297 CHEMBL1081499::N-(2-chlorophenyl)-6-methylpyrazolo[1,5-a]pyridine-3-carboxamide

SMILES: Cc1ccc2c(cnn2c1)C(=O)Nc1ccccc1Cl

InChI Key: InChIKey=XHCRWAPRQCSELF-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311297   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311297
PNG
(CHEMBL1081499 | N-(2-chlorophenyl)-6-methylpyrazol...)
Show SMILES Cc1ccc2c(cnn2c1)C(=O)Nc1ccccc1Cl
Show InChI InChI=1S/C15H12ClN3O/c1-10-6-7-14-11(8-17-19(14)9-10)15(20)18-13-5-3-2-4-12(13)16/h2-9H,1H3,(H,18,20)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair