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BDBM50311314 CHEMBL1078542::N-(2-methoxyphenyl)-6-phenylimidazo[1,2-a]pyridine-3-carboxamide

SMILES: COc1ccccc1NC(=O)c1cnc2ccc(cn12)-c1ccccc1

InChI Key: InChIKey=MXJBXTJDRDZTNZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311314   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311314
PNG
(CHEMBL1078542 | N-(2-methoxyphenyl)-6-phenylimidaz...)
Show SMILES COc1ccccc1NC(=O)c1cnc2ccc(cn12)-c1ccccc1
Show InChI InChI=1S/C21H17N3O2/c1-26-19-10-6-5-9-17(19)23-21(25)18-13-22-20-12-11-16(14-24(18)20)15-7-3-2-4-8-15/h2-14H,1H3,(H,23,25)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair