BDBM50311521 CHEMBL1081556::N-(4-chlorobenzyl)-2-((2S,6S,E)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl)acetamide

SMILES Clc1ccc(CNC(=O)C[C@@H]2C\C=C\CCC(=O)O[C@H](CNC2=O)c2ccccc2)cc1

InChI Key InChIKey=DRDSZZCLAHXSAE-DIQFXESUSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311521   

TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311521(CHEMBL1081556 | N-(4-chlorobenzyl)-2-((2S,6S,E)-5,...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311521(CHEMBL1081556 | N-(4-chlorobenzyl)-2-((2S,6S,E)-5,...)
Affinity DataKd:  570nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed