BDBM50311659 (8R,9S,13S,14S)-2-Bromo-3-hydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one(8R,9S,13S,14S)-2-Bromo-3-hydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one::(8R,9S,13S,14S)-2-bromo-3-hydroxy-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one::CHEMBL189051

SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(O)c(Br)cc34)[C@@H]1CCC2=O

InChI Key InChIKey=JVITVXNLPKMREE-JPVZDGGYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311659   

TargetAromatase(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50311659((8R,9S,13S,14S)-2-Bromo-3-hydroxy-13-methyl-6,7,8,...)
Affinity DataKi:  100nMAssay Description:Competitive inhibition of human aromatase extracted from placental microsomes after 5 mins by Dixon plot analysis in presence of [1beta-3H]ADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311659((8R,9S,13S,14S)-2-Bromo-3-hydroxy-13-methyl-6,7,8,...)
Affinity DataIC50:  233nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50311659((8R,9S,13S,14S)-2-Bromo-3-hydroxy-13-methyl-6,7,8,...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed