BDBM50312528 CHEMBL1086997::N-Butyl-D-galacto-1-deoxynojirimycin

SMILES CCCCN1C[C@H](O)[C@@H](O)[C@@H](O)[C@H]1CO

InChI Key InChIKey=UQRORFVVSGFNRO-XFWSIPNHSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50312528   

TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312528(CHEMBL1086997 | N-Butyl-D-galacto-1-deoxynojirimyc...)
Affinity DataIC50:  460nMAssay Description:Inhibition of sucrase by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312528(CHEMBL1086997 | N-Butyl-D-galacto-1-deoxynojirimyc...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312528(CHEMBL1086997 | N-Butyl-D-galacto-1-deoxynojirimyc...)
Affinity DataIC50:  3.20E+5nMAssay Description:Inhibition of GBA1 (unknown origin) using beta-D-[1-14C]glucocerebroside assessed as 4-methylumbelliferrone by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312528(CHEMBL1086997 | N-Butyl-D-galacto-1-deoxynojirimyc...)
Affinity DataIC50:  300nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312528(CHEMBL1086997 | N-Butyl-D-galacto-1-deoxynojirimyc...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of maltase by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactase/phlorizin hydrolase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312528(CHEMBL1086997 | N-Butyl-D-galacto-1-deoxynojirimyc...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of lactase by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312528(CHEMBL1086997 | N-Butyl-D-galacto-1-deoxynojirimyc...)
Affinity DataIC50:  300nMAssay Description:Inhibition of GBA2 by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312528(CHEMBL1086997 | N-Butyl-D-galacto-1-deoxynojirimyc...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen debranching enzyme(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312528(CHEMBL1086997 | N-Butyl-D-galacto-1-deoxynojirimyc...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of glycogen glycogen de-branching enzyme by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312528(CHEMBL1086997 | N-Butyl-D-galacto-1-deoxynojirimyc...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of GCS by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed