BDBM50312714 (S)-4-cyclohexyl-2-cyclopentyl-3-((S)-fluoro(4-(trifluoromethyl)phenyl)methyl)-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol::CHEMBL1081288

SMILES CC1(C)C[C@H](O)c2c(C1)nc(C1CCCC1)c([C@@H](F)c1ccc(cc1)C(F)(F)F)c2C1CCCCC1

InChI Key InChIKey=BHKIPHICFOJGLD-HOFKKMOUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312714   

TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50312714((S)-4-cyclohexyl-2-cyclopentyl-3-((S)-fluoro(4-(tr...)
Affinity DataIC50:  25nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50312714((S)-4-cyclohexyl-2-cyclopentyl-3-((S)-fluoro(4-(tr...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50312714((S)-4-cyclohexyl-2-cyclopentyl-3-((S)-fluoro(4-(tr...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed