BDBM50312718 CHEMBL479527::torcetrapib
SMILES CCOC(=O)N1[C@H](CC)C[C@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)OC)c2cc(ccc12)C(F)(F)F
InChI Key InChIKey=CMSGWTNRGKRWGS-NQIIRXRSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50312718
Affinity DataIC50: 20nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 18nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of CETP-mediated BODIPY-labeled cholesteryl ester transfer after 45 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of CETP in human whole plasma assessed as reduction in [3H]-CE/HDL transfer incubated for 2.5 hrs by topcount scintillation counting assayMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of CETP in human plasma assessed as transfer of fluorescently labelled cholesteryl ester to VLDL by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of CETP in human plasma measured every 30 mins for 120 mins by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of CETP-mediated [3H]cholesteryl ester transfer activity in human plasma after 2.5 hrs by scintillation counterMore data for this Ligand-Target Pair