BDBM50312745 (S)-N1-(5-(3-cyclopropyl-1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)-3-(4-(trifluoromethyl)phenyl)propane-1,2-diamine::CHEMBL1081437

SMILES N[C@H](CNc1nnc(s1)-c1ccc2[nH]nc(C3CC3)c2c1)Cc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=VSDYUWIOYNTKSO-INIZCTEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312745   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312745((S)-N1-(5-(3-cyclopropyl-1H-indazol-5-yl)-1,3,4-th...)
Affinity DataIC50:  135nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312745((S)-N1-(5-(3-cyclopropyl-1H-indazol-5-yl)-1,3,4-th...)
Affinity DataIC50:  181nMAssay Description:Inhibition of AKT1 after 10 mins by [gamma33]ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed