BDBM50312866 4-(4-(thiophen-2-yl)thiazol-2-ylamino)phenol::CHEMBL1081262::cid_793670

SMILES Oc1ccc(Nc2nc(cs2)-c2cccs2)cc1

InChI Key InChIKey=CYHUWUQCNGKSKF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312866   

TargetProbable nicotinate-nucleotide adenylyltransferase(Staphylococcus aureus subsp. aureus N315)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50312866(4-(4-(thiophen-2-yl)thiazol-2-ylamino)phenol | CHE...)
Affinity DataIC50:  2.83E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50312866(4-(4-(thiophen-2-yl)thiazol-2-ylamino)phenol | CHE...)
Affinity DataIC50:  110nMAssay Description:Inhibition of VCP assessed as conversion of ATP to ADP by enzyme coupled glucokinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50312866(4-(4-(thiophen-2-yl)thiazol-2-ylamino)phenol | CHE...)
Affinity DataEC50:  90nMAssay Description:Inhibition of VCP in human HeLa cells assessed as stabilization of ubiquitin-tagged luciferase after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed