BDBM50312870 CHEMBL1080890::N-aryl-4-aryl-1,3-thiazole-2-amine, 27::N1-(4-(4-chlorophenyl)thiazol-2-yl)benzene-1,4-diamine

SMILES Nc1ccc(Nc2nc(cs2)-c2ccc(Cl)cc2)cc1

InChI Key InChIKey=BUROQFHRHNMPDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312870   

TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50312870(CHEMBL1080890 | N-aryl-4-aryl-1,3-thiazole-2-amine...)
Affinity DataIC50:  80nMAssay Description:Inhibition of VCP assessed as conversion of ATP to ADP by enzyme coupled glucokinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

LigandPNGBDBM50312870(CHEMBL1080890 | N-aryl-4-aryl-1,3-thiazole-2-amine...)
Affinity DataIC50:  160nMpH: 7.4 T: 2°CAssay Description:5-LOX enzyme assay was carried out with some modifications of ferric oxidation of xylenol orange (FOX) assay, which is based on the complex formation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed