BDBM50313291 (1S,4S)-2-(4-tert-butylphenylsulfonyl)-2,5-diazabicyclo[2.2.1]heptane::CHEMBL1081452

SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1C[C@@H]2C[C@H]1CN2

InChI Key InChIKey=NLRPQPISQZRZTP-STQMWFEESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313291   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313291((1S,4S)-2-(4-tert-butylphenylsulfonyl)-2,5-diazabi...)
Affinity DataIC50:  156nMAssay Description:Displacement of [3H]cortisone from mouse 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313291((1S,4S)-2-(4-tert-butylphenylsulfonyl)-2,5-diazabi...)
Affinity DataIC50:  4.40E+3nMAssay Description:Displacement of [3H]cortisone from human 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed