BDBM50313858 CHEMBL1084422::c(R)-5-chloro-1-(1-cyclopropylethyl)-3-(2-methyl-5,7-dihydrofuro[3,4-b]pyridin-3-ylamino)pyrazin-2(1H)-one

SMILES C[C@H](C1CC1)n1cc(Cl)nc(Nc2cc3COCc3nc2C)c1=O

InChI Key InChIKey=KFIJAXDSLJTZBJ-SNVBAGLBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313858   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50313858(CHEMBL1084422 | c(R)-5-chloro-1-(1-cyclopropylethy...)
Affinity DataIC50:  740nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed