BDBM50314077 5-(p-tolylthio)-9H-pyrimido[4,5-b]indole-2,4-diamine::CHEMBL1093100::US9422297, AAG-148-311
SMILES Cc1ccc(Sc2cccc3[nH]c4nc(N)nc(N)c4c23)cc1
InChI Key InChIKey=IMNBYLUXBBXZIY-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50314077
Affinity DataIC50: 390nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: >2.60E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of EGFR in human A431 cells by phosphotyrosine cell-based ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 5.63E+4nMAssay Description:Inhibition of VEGFR2 in human U251 cells by phosphotyrosine cell-based ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: >3.10E+4nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 4.03E+4nMAssay Description:Inhibition of PDGFRbeta in human SF539 cells by phosphotyrosine cell-based ELISAMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 3.96E+4nMAssay Description:Inhibition of Flt3 activity in human MV 3:11 cells by phosphotyrosine cell-based ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of VEGFR1 in human A498 cells by phosphotyrosine cell-based ELISAMore data for this Ligand-Target Pair