BindingDB logo
myBDB logout

BDBM50314408 3-amino-4-methyl-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide::CHEMBL1091709

SMILES: Cc1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12

InChI Key: InChIKey=DEDIWXVHCRLIOE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314408   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314408
PNG
(3-amino-4-methyl-5,6,7,8,9,10-hexahydrocycloocta[b...)
Show SMILES Cc1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C15H19N3OS/c1-8-9-6-4-2-3-5-7-10(9)18-15-11(8)12(16)13(20-15)14(17)19/h2-7,16H2,1H3,(H2,17,19)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair