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BDBM50314415 4-(3-amino-2-carbamoyl-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridin-4-yl)benzoic acid::CHEMBL1090045

SMILES: NC(=O)c1sc2nc3CCCCCCc3c(-c3ccc(cc3)C(O)=O)c2c1N

InChI Key: InChIKey=GBWKMOBOMPRFBT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314415   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase EEF2K


(Homo sapiens (Human))
BDBM50314415
PNG
(4-(3-amino-2-carbamoyl-5,6,7,8,9,10-hexahydrocyclo...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccc(cc3)C(O)=O)c2c1N
Show InChI InChI=1S/C21H21N3O3S/c22-17-16-15(11-7-9-12(10-8-11)21(26)27)13-5-3-1-2-4-6-14(13)24-20(16)28-18(17)19(23)25/h7-10H,1-6,22H2,(H2,23,25)(H,26,27)
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Similars

Article
PubMed
n/an/a 860n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair