BindingDB logo
myBDB logout

BDBM50314419 (E)-3-amino-4-(2-(furan-2-yl)vinyl)-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide::CHEMBL1091829

SMILES: NC(=O)c1sc2nc3CCCCCCc3c(\C=C\c3ccco3)c2c1N

InChI Key: InChIKey=GAPXEUQVAPEONE-MDZDMXLPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314419   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314419
PNG
((E)-3-amino-4-(2-(furan-2-yl)vinyl)-5,6,7,8,9,10-h...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(\C=C\c3ccco3)c2c1N
Show InChI InChI=1S/C20H21N3O2S/c21-17-16-14(10-9-12-6-5-11-25-12)13-7-3-1-2-4-8-15(13)23-20(16)26-18(17)19(22)24/h5-6,9-11H,1-4,7-8,21H2,(H2,22,24)/b10-9+
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 320n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair