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BDBM50314420 3-amino-4-(3-methylthiophen-2-yl)-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide::CHEMBL1091830

SMILES: Cc1ccsc1-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12

InChI Key: InChIKey=JFWUTNVXUNPNJU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314420   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314420
PNG
(3-amino-4-(3-methylthiophen-2-yl)-5,6,7,8,9,10-hex...)
Show SMILES Cc1ccsc1-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C19H21N3OS2/c1-10-8-9-24-16(10)13-11-6-4-2-3-5-7-12(11)22-19-14(13)15(20)17(25-19)18(21)23/h8-9H,2-7,20H2,1H3,(H2,21,23)
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Article
PubMed
n/an/a 460n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair