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BDBM50314430 3-amino-4-(5-ethylfuran-2-yl)-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide::CHEMBL1091075

SMILES: CCc1ccc(o1)-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12

InChI Key: InChIKey=WFLFCWLGESAVJS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314430   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314430
PNG
(3-amino-4-(5-ethylfuran-2-yl)-5,6,7,8,9,10-hexahyd...)
Show SMILES CCc1ccc(o1)-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C20H23N3O2S/c1-2-11-9-10-14(25-11)15-12-7-5-3-4-6-8-13(12)23-20-16(15)17(21)18(26-20)19(22)24/h9-10H,2-8,21H2,1H3,(H2,22,24)
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Article
PubMed
n/an/a 660n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair