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BDBM50314444 2-(4-chlorophenyl)-10-thia-5,7,12-triazatetracyclo[11.7.0.0^{3,11}.0^{4,9}]icosa-1(13),2,4(9),5,7,11-hexaen-8-amine::CHEMBL1094018

SMILES: Nc1ncnc2c1sc1nc3CCCCCCCc3c(-c3ccc(Cl)cc3)c21

InChI Key: InChIKey=JGWFGPLJAWDQNW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314444   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase EEF2K


(Homo sapiens (Human))
BDBM50314444
PNG
(2-(4-chlorophenyl)-10-thia-5,7,12-triazatetracyclo...)
Show SMILES Nc1ncnc2c1sc1nc3CCCCCCCc3c(-c3ccc(Cl)cc3)c21
Show InChI InChI=1S/C22H21ClN4S/c23-14-10-8-13(9-11-14)17-15-6-4-2-1-3-5-7-16(15)27-22-18(17)19-20(28-22)21(24)26-12-25-19/h8-12H,1-7H2,(H2,24,25,26)
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Similars

Article
PubMed
n/an/a 110n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair