BDBM50314915 1'-(1H-indazol-7-ylcarbonyl)-6-methylspiro[chromene-2,4'-piperidin]-4(3H)-one::1'-(1H-indazole-7-carbonyl)-6-methylspiro[chroman-2,4'-piperidin]-4-one::CHEMBL1090121

SMILES Cc1ccc2OC3(CCN(CC3)C(=O)c3cccc4cn[nH]c34)CC(=O)c2c1

InChI Key InChIKey=IKCMGTBANLMNNP-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314915   

TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314915(1'-(1H-indazol-7-ylcarbonyl)-6-methylspiro[chromen...)
Affinity DataIC50:  641nMAssay Description:Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314915(1'-(1H-indazol-7-ylcarbonyl)-6-methylspiro[chromen...)
Affinity DataIC50:  634nMAssay Description:Inhibition of rat liver ACC1 after 7 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed