BDBM50315084 1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazin-2-yl)phenyl)-3-(4-((dimethylamino)methyl)phenyl)urea::CHEMBL1093182

SMILES C[C@@H]1COCCN1c1nc(nc(n1)-c1ccc(NC(=O)Nc2ccc(CN(C)C)cc2)cc1)N1CCOC[C@H]1C

InChI Key InChIKey=HJEBTNWYYOYFPM-NHCUHLMSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315084   

LigandPNGBDBM50315084(1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazi...)
Affinity DataIC50:  413nMAssay Description:Inhibition of PI3Kalpha assessed as PIP3 accumulation after 24 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315084(1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazi...)
Affinity DataIC50:  2nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed