BDBM50315084 1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazin-2-yl)phenyl)-3-(4-((dimethylamino)methyl)phenyl)urea::CHEMBL1093182
SMILES C[C@@H]1COCCN1c1nc(nc(n1)-c1ccc(NC(=O)Nc2ccc(CN(C)C)cc2)cc1)N1CCOC[C@H]1C
InChI Key InChIKey=HJEBTNWYYOYFPM-NHCUHLMSSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50315084
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 413nMAssay Description:Inhibition of PI3Kalpha assessed as PIP3 accumulation after 24 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair