BDBM50315331 1-(8-chlorobenzofuro[3,2-d]pyrimidin-4-yl)-N-methylazetidin-3-amine::CHEMBL1091569

SMILES CNC1CN(C1)c1ncnc2c3cc(Cl)ccc3oc12

InChI Key InChIKey=OYMJTEMKKMATMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315331   

TargetHistamine H4 receptor(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50315331(1-(8-chlorobenzofuro[3,2-d]pyrimidin-4-yl)-N-methy...)
Affinity DataIC50:  76nMAssay Description:Inverse agonist activity at human histamine H4 receptor assessed as inhibition of [35S]GTPgammaS binding after 15 mins by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50315331(1-(8-chlorobenzofuro[3,2-d]pyrimidin-4-yl)-N-methy...)
Affinity DataIC50:  87nMAssay Description:Displacement of [3H]histamine dihydrochloride from human histamine H4 receptor after 2.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed