BDBM50315399 (R)-2-((2-oxo-3,4-dihydroquinolin-1(2H)-yl)methyl)-6,8-dihydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one::CHEMBL1090847
SMILES O=C1Nc2ncccc2[C@]11Cc2cc3ccc(CN4C(=O)CCc5ccccc45)nc3cc2C1
InChI Key InChIKey=GCWWLFCJNPWAEP-MUUNZHRXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50315399
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP production in t...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair