BDBM50315469 3-(3-hydroxy-1-(naphthalen-2-ylmethyl)-2-oxoindolin-7-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide::CHEMBL1093125

SMILES OC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(F)c(F)cc1F

InChI Key InChIKey=FBMLUXABXAEURE-ZHACJKMWSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50315469   

TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315469(3-(3-hydroxy-1-(naphthalen-2-ylmethyl)-2-oxoindoli...)
Affinity DataIC50: >2.00E+4nMAssay Description:Binding affinity to human EP2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315469(3-(3-hydroxy-1-(naphthalen-2-ylmethyl)-2-oxoindoli...)
Affinity DataIC50:  8.70E+3nMAssay Description:Binding affinity to human EP4 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315469(3-(3-hydroxy-1-(naphthalen-2-ylmethyl)-2-oxoindoli...)
Affinity DataIC50:  9.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315469(3-(3-hydroxy-1-(naphthalen-2-ylmethyl)-2-oxoindoli...)
Affinity DataIC50: >2.00E+4nMAssay Description:Binding affinity to human IP receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315469(3-(3-hydroxy-1-(naphthalen-2-ylmethyl)-2-oxoindoli...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315469(3-(3-hydroxy-1-(naphthalen-2-ylmethyl)-2-oxoindoli...)
Affinity DataIC50: >2.00E+4nMAssay Description:Binding affinity to human FP receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed