BDBM50315524 3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide::CHEMBL1089491

SMILES CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(F)c(F)cc1F

InChI Key InChIKey=LOXTXYPNYNYQRX-SOFGYWHQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315524   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315524(3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315524(3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...)
Affinity DataIC50:  4.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed