BDBM50315984 3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-phenoxyethoxy)phenyl)-N-(3,4-difluorophenylsulfonyl)propanamide::CHEMBL1092976

SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(Cn2cccn2)cc1OCCOc1ccccc1

InChI Key InChIKey=OMDGJDQUQYVXBQ-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50315984   

TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315984(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-phenoxyethoxy)...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315984(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-phenoxyethoxy)...)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315984(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-phenoxyethoxy)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315984(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-phenoxyethoxy)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315984(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-phenoxyethoxy)...)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed