BDBM50316116 6-Allyl-(methyl)-amino-3-benzyl-2-methylthioquinazolin-4(3H)-one::CHEMBL1090896

SMILES CSc1nc2ccc(cc2c(=O)n1Cc1ccccc1)N(C)CC=C

InChI Key InChIKey=ZENXLZOOOONYJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316116   

TargetDihydrofolate reductase(Homo sapiens (Human))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50316116(6-Allyl-(methyl)-amino-3-benzyl-2-methylthioquinaz...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human DHFR after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50316116(6-Allyl-(methyl)-amino-3-benzyl-2-methylthioquinaz...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of bovine DHFR after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed