BDBM50316126 Bleph-10::Bleph-30::Blephamide::CHEMBL455::Cetamide::Cetapred::FML-S::Klaron::Metimyd::N-Acetyl-4-amino-benzenesulfonamide::Ocusulf-10::Ocusulf-30::Predamide::Predsulfair::SULF-10::SULF-15::SULFACETAMIDE::Sulfacel-15::Sulfacetamide, 1::Sulfair-15::Sulphacetamide::Sulphrin::Sulster::Sulten-10::Vasocidin

SMILES CC(=O)NS(=O)(=O)c1ccc(N)cc1

InChI Key InChIKey=SKIVFJLNDNKQPD-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50316126   

TargetSerum paraoxonase/arylesterase 1(Homo sapiens (Human))
AtatÜRk University

LigandPNGBDBM50316126(Bleph-10 | Bleph-30 | Blephamide | CHEMBL455 | Cet...)
Affinity DataKi:  8.60E+4nM IC50:  1.80E+5nMAssay Description:The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50316126(Bleph-10 | Bleph-30 | Blephamide | CHEMBL455 | Cet...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50316126(Bleph-10 | Bleph-30 | Blephamide | CHEMBL455 | Cet...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of bovine DHFR after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMultidrug and toxin extrusion protein 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50316126(Bleph-10 | Bleph-30 | Blephamide | CHEMBL455 | Cet...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50316126(Bleph-10 | Bleph-30 | Blephamide | CHEMBL455 | Cet...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human DHFR after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed