BDBM50316256 CHEMBL1094981::isopropyl 4-[6-(4-{[(2-fluoroethyl)carbamoyl]amino}phenyl)-4-morpholin-4-yl-1Hpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate

SMILES CC(C)OC(=O)N1CCC(CC1)n1ncc2c(nc(nc12)-c1ccc(NC(=O)NCCF)cc1)N1CCOCC1

InChI Key InChIKey=WQJYOLLPRXNMCU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316256   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316256(CHEMBL1094981 | isopropyl 4-[6-(4-{[(2-fluoroethyl...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316256(CHEMBL1094981 | isopropyl 4-[6-(4-{[(2-fluoroethyl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ATR by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50316256(CHEMBL1094981 | isopropyl 4-[6-(4-{[(2-fluoroethyl...)
Affinity DataIC50:  3.77E+3nMAssay Description:Inhibition of PI3Kgamma by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50316256(CHEMBL1094981 | isopropyl 4-[6-(4-{[(2-fluoroethyl...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed