BDBM50316281 1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl}-3-ethylurea::CHEMBL1098306

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(C3CCN(Cc4ccccc4)CC3)c2n1

InChI Key InChIKey=UQBDVXGNVUOMQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316281   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316281(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50316281(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50:  257nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed