BDBM50316309 ((2R,3S,4R,5R)-5-(2-Amino-7-(2-chlorobenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1095941

SMILES Nc1nc2n(c[n+](Cc3ccccc3Cl)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O

InChI Key InChIKey=ZUAWTVARTFVXMM-XNIJJKJLSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316309   

TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50316309(((2R,3S,4R,5R)-5-(2-Amino-7-(2-chlorobenzyl)-6-oxo...)
Affinity DataIC50:  5.45E+4nMAssay Description:Competitive inhibition of [3H]m7-GTP binding to human FLAG-His6 tagged eIF4E expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 4E(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316309(((2R,3S,4R,5R)-5-(2-Amino-7-(2-chlorobenzyl)-6-oxo...)
Affinity DataKd:  2.24E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed