BDBM50316651 1-(2-ethoxyethyl)-3-ethyl-N-phenyl-5-(piperazin-1-yl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine::CHEMBL1094544

SMILES CCOCCn1nc(CC)c2nc(nc(Nc3ccccc3)c12)N1CCNCC1

InChI Key InChIKey=XIEAYYVLHOZOEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316651   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316651(1-(2-ethoxyethyl)-3-ethyl-N-phenyl-5-(piperazin-1-...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed