BDBM50316667 1-(2-ethoxyethyl)-3-ethyl-N5-methyl-N7-(4-methylpyridin-2-yl)-N5-(pyrrolidin-3-yl)-1H-pyrazolo[4,3-d]pyrimidine-5,7-diamine::CHEMBL1094830

SMILES CCOCCn1nc(CC)c2nc(nc(Nc3cc(C)ccn3)c12)N(C)C1CCNC1

InChI Key InChIKey=FDZWPMLGNKIMOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316667   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316667(1-(2-ethoxyethyl)-3-ethyl-N5-methyl-N7-(4-methylpy...)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed