BDBM50316771 (Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-propylimino-3-o-tolyl-thiazolidin-4-one::CHEMBL1096872

SMILES CCC\N=C1/S\C(=C/c2ccc(O)c(Cl)c2)C(=O)N1c1ccccc1C

InChI Key InChIKey=BQKSAYBFUIEOBO-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50316771   

TargetSphingosine 1-phosphate receptor 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316771((Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-propyli...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human recombinant S1P1 receptor expressed in CHO cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316771((Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-propyli...)
Affinity DataIC50: 40nMAssay Description:Immunomodulatory activity at human S1PR1 expressed in CHO-K1 EDG1 beta-arrestin cells assessed as stimulation of beta-arrestin recruitment incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50316771((Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-propyli...)
Affinity DataEC50:  81nMAssay Description:Agonist activity at human recombinant S1P3 receptor expressed in CHO cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed