BDBM50316792 2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethylphenyl)]benzyl-1H-indole-3-yl}ethanamine hydrochloride::CHEMBL1094195

SMILES NCCc1cn(Cc2ccc(cc2)-c2cccc(c2)C(F)(F)F)c2ccc(OCCc3ccc(O)cc3)cc12

InChI Key InChIKey=KVZGXHXBYQNWHP-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50316792   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of EGFR after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  1.50E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 250 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  3.08E+3nMAssay Description:Noncompetitive inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA in presence of 250 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  1.12E+3nMAssay Description:Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  1.48E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of VEGFR2 after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  3.01E+3nMAssay Description:Inhibition of VEGFR3 after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  1.11E+3nMAssay Description:Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  3.01E+3nMAssay Description:Noncompetitive inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  2.98E+3nMAssay Description:Noncompetitive inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  1.56E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  1.02E+3nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 250 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  1.07E+3nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  1.07E+3nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  1.12E+3nMAssay Description:Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316792(2-{5-(4-Hydroxyphenethoxy)-1-[4-(3-trifluoromethyl...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of IGF1R after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed