BDBM50317213 (2R)-N-(adamantan-2-yl)-1-(cyclopentylmethyl)pyrrolidine-2-carboxamide::CHEMBL1096870

SMILES O=C(NC1C2CC3CC(C2)CC1C3)[C@H]1CCCN1CC1CCCC1

InChI Key InChIKey=VUHCMAVSZJDZHF-RDOIFFKNSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317213   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317213((2R)-N-(adamantan-2-yl)-1-(cyclopentylmethyl)pyrro...)
Affinity DataKi:  1nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317213((2R)-N-(adamantan-2-yl)-1-(cyclopentylmethyl)pyrro...)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed