BDBM50317222 (2R)-N-(adamantan-2-yl)-1-(2-hydroxyethyl)pyrrolidine-2-carboxamide::CHEMBL1098160

SMILES OCCN1CCC[C@@H]1C(=O)NC1C2CC3CC(C2)CC1C3

InChI Key InChIKey=NJIXITKIPGUHHS-BAPHQMLMSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317222   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317222((2R)-N-(adamantan-2-yl)-1-(2-hydroxyethyl)pyrrolid...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317222((2R)-N-(adamantan-2-yl)-1-(2-hydroxyethyl)pyrrolid...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed