BDBM50317965 CHEMBL1099096::N-hydroxy-3-(3-(1-phenethyl-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide

SMILES ONC(=O)\C=C\c1cccc(c1)-c1nc2ccccc2n1CCc1ccccc1

InChI Key InChIKey=OMOXBIORXCIFMM-BUHFOSPRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317965   

TargetHistone deacetylase 8(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317965(CHEMBL1099096 | N-hydroxy-3-(3-(1-phenethyl-1H-ben...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317965(CHEMBL1099096 | N-hydroxy-3-(3-(1-phenethyl-1H-ben...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317965(CHEMBL1099096 | N-hydroxy-3-(3-(1-phenethyl-1H-ben...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed