BDBM50317983 CHEMBL1099057::N-hydroxy-3-(3-(1-(2-(piperidin-1-yl)ethyl)-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide

SMILES ONC(=O)\C=C\c1cccc(c1)-c1nc2ccccc2n1CCN1CCCCC1

InChI Key InChIKey=DWNRYQMKYULULJ-VAWYXSNFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317983   

TargetHistone deacetylase 8(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317983(CHEMBL1099057 | N-hydroxy-3-(3-(1-(2-(piperidin-1-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317983(CHEMBL1099057 | N-hydroxy-3-(3-(1-(2-(piperidin-1-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317983(CHEMBL1099057 | N-hydroxy-3-(3-(1-(2-(piperidin-1-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed