BDBM50319176 4-Isopropylsulfonylamino-8-methoxy-3-methyl-1-propyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine::CHEMBL1083775

SMILES CCCc1nc(C)c2c(NS(=O)(=O)C(C)C)nc3ccc(OC)nc3n12

InChI Key InChIKey=KZPGJARUFMBJIT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319176   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Biotie Therapies

Curated by ChEMBL
LigandPNGBDBM50319176(4-Isopropylsulfonylamino-8-methoxy-3-methyl-1-prop...)
Affinity DataIC50:  132nMAssay Description:Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed