BDBM50319969 CHEMBL1085781::N-benzyl-2-morpholinopyrimidin-4-amine

SMILES C(Nc1ccnc(n1)N1CCOCC1)c1ccccc1

InChI Key InChIKey=PKTXFNWLILBNOJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319969   

TargetAcetylcholinesterase(Electric eel)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319969(CHEMBL1085781 | N-benzyl-2-morpholinopyrimidin-4-a...)
Affinity DataIC50:  500nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarboxylic ester hydrolase(Horse)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319969(CHEMBL1085781 | N-benzyl-2-morpholinopyrimidin-4-a...)
Affinity DataIC50:  6.83E+4nMAssay Description:Inhibition of equine BChE incubated with compounf for 5 mins before addition of substrate S-butyrylthiocholine iodide by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319969(CHEMBL1085781 | N-benzyl-2-morpholinopyrimidin-4-a...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human AChE incubated with compounf for 5 mins before addition of substrate acetylthiocholine iodide by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319969(CHEMBL1085781 | N-benzyl-2-morpholinopyrimidin-4-a...)
Affinity DataIC50:  6.83E+4nMAssay Description:Inhibition of equine serum BuChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed