BDBM50320700 1-[2-chloro-2-(4-fluorophenyl)ethyl]-N-(3-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1165511
SMILES Fc1ccc(cc1)C(Cl)Cn1ncc2c(Nc3cccc(F)c3)ncnc12
InChI Key InChIKey=AAMZEJILAVQVEW-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50320700
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institute Of Molecular Genetics Igm-Cnr
Curated by ChEMBL
Institute Of Molecular Genetics Igm-Cnr
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of histidine-tagged human recombinant SRC expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institute Of Molecular Genetics Igm-Cnr
Curated by ChEMBL
Institute Of Molecular Genetics Igm-Cnr
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of histidine-tagged human recombinant SRC expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Institute Of Molecular Genetics Igm-Cnr
Curated by ChEMBL
Institute Of Molecular Genetics Igm-Cnr
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Inhibition of histidine-tagged human recombinant ABL expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Institute Of Molecular Genetics Igm-Cnr
Curated by ChEMBL
Institute Of Molecular Genetics Igm-Cnr
Curated by ChEMBL
Affinity DataKi: 732nMAssay Description:Binding affinity to recombinant wild type human Abl using abitide as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Institute Of Molecular Genetics Igm-Cnr
Curated by ChEMBL
Institute Of Molecular Genetics Igm-Cnr
Curated by ChEMBL
Affinity DataKi: 750nMAssay Description:Inhibition of histidine-tagged human recombinant ABL expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Institute Of Molecular Genetics Igm-Cnr
Curated by ChEMBL
Institute Of Molecular Genetics Igm-Cnr
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Mixed-type inhibition of histidine-tagged human recombinant ABL expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins b...More data for this Ligand-Target Pair