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BDBM50321378 2-(3-(4-methoxyphenylthio)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid::CHEMBL1171125

SMILES: COc1ccc(SC2CCc3ccccc3N(CC(O)=O)C2=O)cc1

InChI Key: InChIKey=DKNGJBYTIKXWCZ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321378   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
3-phosphoinositide dependent protein kinase-1


(Homo sapiens (human))
BDBM50321378
PNG
(2-(3-(4-methoxyphenylthio)-2-oxo-2,3,4,5-tetrahydr...)
Show SMILES COc1ccc(SC2CCc3ccccc3N(CC(O)=O)C2=O)cc1
Show InChI InChI=1S/C19H19NO4S/c1-24-14-7-9-15(10-8-14)25-17-11-6-13-4-2-3-5-16(13)20(19(17)23)12-18(21)22/h2-5,7-10,17H,6,11-12H2,1H3,(H,21,22)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 5.30E+4n/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Displacement of PIFtide from His-tagged PDK1 by HTRF assay


Bioorg Med Chem Lett 20: 3897-902 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.019
BindingDB Entry DOI: 10.7270/Q2Z60Q1H
More data for this
Ligand-Target Pair