BDBM50321539 CHEMBL1170129::N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-4-(methylsulfonyl)benzamide

SMILES CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccc(cc3)S(C)(=O)=O)sc12

InChI Key InChIKey=JIBPVUZCHLCLJB-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50321539   

TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321539(CHEMBL1170129 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321539(CHEMBL1170129 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataKi:  92nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321539(CHEMBL1170129 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321539(CHEMBL1170129 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataIC50:  36nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of adenosine-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed