BDBM50321906 (Z)-1-[2-Oxo-3-(1H-pyrrol-2-ylmethylene)-2,3-dihydro-1H-indol-6-yl]-3-(p-tolyl)-urea::CHEMBL1172815

SMILES Cc1ccc(NC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1

InChI Key InChIKey=RAOCKIXJWYDYCO-WQRHYEAKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50321906   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321906((Z)-1-[2-Oxo-3-(1H-pyrrol-2-ylmethylene)-2,3-dihyd...)
Affinity DataIC50:  14nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321906((Z)-1-[2-Oxo-3-(1H-pyrrol-2-ylmethylene)-2,3-dihyd...)
Affinity DataIC50:  147nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321906((Z)-1-[2-Oxo-3-(1H-pyrrol-2-ylmethylene)-2,3-dihyd...)
Affinity DataIC50:  272nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50321906((Z)-1-[2-Oxo-3-(1H-pyrrol-2-ylmethylene)-2,3-dihyd...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed